HMP also known as the Pentose phosphate pathway. Consists of two irreversible oxidative rxs followed by a series of reversible Glucose 1 phosphate promotes compartmentalization of glycogen with the pentose phosphate pathway in CD8+ memory T cells: Molecular Cell Pentose Phosphate Pathway (Part 4 of 5) NADPH and Glutathione as Anti Oxidants Metabolism: The pentose phosphate pathway and G6PD deficiency (practice) Khan Academy Pentose Phosphate Pathway made simple. This pathway has two major jobs: Generate NADPH Produce ribose 5 phosphate NADPH protects cells from oxidative stress and supports fatty acid, cholesterol, steroid, nitric oxide, and respiratory burst