This was melanosis coli in a 75M with a long standing type 2 diabetes and chronic constipation in the form of heavily pigmented mucosa, resembling leopard skin, from the cecum through the ascending Melanosis Coli El Atlas Gastrointestinal gastrointestinalatlas.com Hepatitis C Genotype 4: Genotypic Diversity, Epidemiological Profile, and Clinical Relevance of Subtypes in Saudi Arabia Melanosis coli Wikipedia This is a very rare case of metastatic oral mucosal melanoma to the colon with an unusual presentation mimicking melanosis coli. The colonoscopy findings show no mass effect but multiple hyperpigmented lesions