Disruption in glutathione metabolism and altered energy production in the liver and kidney after ischemic acute kidney injury in mice Scientific Reports Interleukin 4 deficiency protects mice from acetaminophen induced liver injury and inflammation by prevention of glutathione depletion Inflammation Research Springer Nature Link A 48 hour fast can turn standard Paracetamol into acute liver failure. Fasting depletes Glutathione, leaving the liver defenseless against toxic NAPQI. Review the latest guidelines on BMJ Best Practice: https: bestpractice.bmj.com topics en us 1010 Glutathione is a powerful antioxidant that helps our liver detoxify things that go through it. Many think taking oral glutathione will help replenish and optimize liver health, but they don't actually end Glutathione IV Liver Detox for Rapid Liver Repair and Cleansing