Does ibuprofen deplete glutathione? Dose dependent effects of acetaminophen and ibuprofen on mitochondrial respiration of human platelets Molecular and Cellular Biochemistry Springer Nature Link Common Medications Can Deplete Vital Nutrients! From birth control pills to statins and antidepressants many meds drain your body of essential vitamins and minerals. Support your body with Ibuprofen administration attenuates serum TNF levels, hepatic glutathione depletion, hepatic apoptosis and mouse mortality after Fas stimulation ScienceDirect What is glutathione and why must we protect patient access to it?