Glutathione Conjugate an overview ScienceDirect Topics GSH reduces NAPQI, the metabolite responsible for hepatotoxicity in acetaminophen toxicity. Toxic doses increase oxidation into NAPQI, overwhelming glutathione. How does ethanol interfere with acetaminophen metabolism? Image: https: t.co 6EY9dIwLXY 16 Phase II reactions Conjugation with GSH paracetamol Full article: Interactions of glutathione transferases with 4 hydroxynonenal The Glutathione System: A Journey from Cyanobacteria to Higher Eukaryotes
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glutathione conjugation reaction Scheme 1. Two pathways for glutathione conjugation to reactive