Does size matter? Historically, a bigger needle gauge was considered better to prevent damage to red blood cells. However, our recent guidelines recommend using smaller gauge needles (2325 G) for all Vitamin B12 Injections Preferred Healthcare Vitamin B12 Injections Administering a Intramuscular B12 Injection : 5 Steps Instructables How to Administer an Intramuscular Injection at Home
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