Individuals with MTHFR mutations and slow COMT activity can generally take N acetylcysteine (NAC) and glutathione, but there are some important considerations: ## N Acetylcysteine (NAC) * **Benefits**: NAC supports the production of glutathione, NAC & Glutathione: The Ultimate Antioxidants for Immunity & Detoxification NAC Pure Powder Glutathione & Cellular Health Support* NOW Foods Redox dependent antioxidant mechanisms of NAC. Intracellular GSH is Download Scientific Diagram DID YOU KNOW NAC is a precursor to glutathione, the master antioxidant? This means it boosts your body's natural detox abilities, combats oxidative stress, and promotes overall immune health. Support your body